Compositions are provided comprising recombinant variants of the human clotting Factor Xa. Such compositions include a wide variety of isoforms and post-translational modifications of FXa and are useful for treating subjects in need of hemostasis.本發明提供包含重組人凝血因子Xa(FXa)變異體之組成物。該等組成物包括FXa之多種同功型及轉譯後修飾體且可用於治療需要止血之個體。