compositions comprising heterogeneous populations of human recombinant coagulation factor xa proteins, their uses and method of purifying a variant factor xa protein.
JASON C. ROUSE,KEITH A. JOHNSON,MARY BETH SWITZER,MICHAEL ANTHONY JANKOWSKI,MICHAEL SHAMASHKIN,PENELOPE JANE SHARPE,STACEY B. WESTON,WENDY CAROL PIACENZA
申请号：
BR112016005899
公开号：
BR112016005899A8
申请日:
2014.09.16
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
The present invention relates to compositions comprising recombinant human coagulation factor xa variants. Such compositions include a wide variety of isoforms and post-translational modifications of fxa and are useful for treating individuals in need of hemostasis.a presente invenção refere-se a composições que compreendem vari-antes recombinantes do fator xa de coagulação humana. tais composições incluem uma ampla variedade de isoformas e modificações pós-traducionais de fxa e são úteis para tratamento de indivíduos com necessidade de hemóstase.
