Nicholas James Devereux;Thomas Anthony Hunt;Stephen Paul Collingwood;Catherine Howsham;Peter Hunt
发明人:
Stephen Paul Collingwood,Nicholas James Devereux,Catherine Howsham,Peter Hunt,Thomas Anthony Hunt
申请号：
US12995647
公开号：
US08236808B2
申请日:
2009.06.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A compound of Formula Ior a hydrate or solvate thereof, where R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
