Gurdip Bhalay,Lee Edwards,Catherine Howsham,Peter Hunt,Nichola Smith
申请号:
US13232175
公开号:
US20120071479A1
申请日:
2011.09.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Compounds of Formula I:and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 have the meanings as indicated in the specification, are useful for treating diseases mediated by blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.