CRAIG A. ROSEN,STEVEN M. RUBEN,WILLIAM A. HASELTINE
申请号：
PT02799966
公开号：
PT1463751E
申请日:
2002.12.23
申请国别(地区):
PT
年份:
2013
代理人:
摘要：
The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention. The fusion protein may comprise a hybrid (human serum albumin)/Kex2 leader sequence followed by a mature albumin fused to the N-terminus of mature interferon alpha-2b.
