Bilodeau, Mark T.,Kadiyala, Sudhakar,Shinde, Rajesh,White, Brian,Wooster, Richard,Barder, Timothy Edward,Moreau, Benoit
申请号：
AU2013369982
公开号：
AU2013369982A1
申请日:
2013.12.30
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
Particles, including nanoparticles and microparticles, and pharmaceutical formulations thereof, containing conjugates of an active agent such as a therapeutic, prophylactic, or diagnostic agent attached to a targeting moiety via a linker have been designed which can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer or infectious diseases.
