MATHEWS, Christopher John,FINNEY, John,SCUTT, James Nicholas,ROBINSON, Louisa,DELANEY, John Stephen
申请号：
ES10700265
公开号：
ES2640592T3
申请日:
2010.01.18
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound of formula I ** Formula ** wherein A is phenyl, naphthyl, pyridyl, pyrazinyl, pyrimidinyl, pyridazinyl, benzothiazolyl, benzoxazolyl, cinolinyl, quinolinyl, quinazolinyl, quinoxalinyl or benzotriazinyl, in each case substituted by halogen, methyl, ethyl , trifluoromethyl, methoxy, difluoromethoxy, trifluoromethoxy, nitro or cyano； R1 is methyl, ethyl, n-propyl, cyclopropyl, halogen, halomethoxy or haloethoxy, R2 and R3 are hydrogen； and R4, R5, R6 and R7 are, independently of each other, hydrogen, halogen, optionally substituted C1-C6 alkyl, optionally substituted C3-C7 cycloalkyl, optionally substituted C2-C6 alkenyl, optionally substituted C5-C7 cycloalkenyl, optionally substituted C2-C6 alkynyl, optionally substituted C1-C6 alkoxy, optionally substituted C3-C7 cycloalkyloxy, optionally substituted C1-C6thio alkyl, optionally substituted C1-C6sulfinyl alkyl, optionally substituted C1-C6 alkyl sulfonyl, optionally substituted aryl, optionally substituted aryloxy, optionally substituted arylthio, arylsulfinyl, optionally substituted optionally substituted arylsulfonyl, optionally substituted heterocyclyl, optionally substituted heterocyclyloxy, optionally substituted heterocyclyl, optionally substituted heterocyclylsulfinyl, optionally substituted heterocyclylsulfonyl, optionally substituted heteroaryl, optionally substituted heteroaryloxy, heteroari optionally substituted lithium, optionally substituted heteroarylsulfinyl, optionally substituted heteroarylsulfonyl, cyano or amino； or R4 and R5, or R6 and R7, together with the atoms to which they are attached, form an optionally substituted saturated or unsaturated carbocyclyl or heterocyclyl, wherein the heterocycle contains one or two heteroatoms selected from nitrogen, oxygen and sulfur； or R5 and R6, together with the atoms to which they are attached, form an optionally substituted saturated or unsaturated carbocyclyl or heterocyclyl, wherein the heterocycle contains one or two heteroatoms selected fr
