WILLIAM M. CANFIELD,RODNEY J. MORELAND,MARIKO KUDO
申请号:
MX2013012345
公开号:
MX2013012345A
申请日:
2012.04.20
申请国别(地区):
MX
年份:
2015
代理人:
摘要:
A modified human acid alpha-glucosidase polypeptide having increased hydrophobicity at or near the N- terminal 70 kDa processing site is provided, as well as methods of making and using the modified human acid alpha-glucosidase to treat glycogen storage disorders.Se proporciona un polipéptido de alfa-glucosidasa ácida humana modificada, así como métodos para producir y usar la alfa-glucosidasa ácida humana modificada para tratar una glucogenosis.