President and Fellows of Harvard College;Dana-Farber Cancer Institute, Inc.
发明人:
Jeffrey Charles Way,Avram Lev Robinson-Mosher,Thomas M. Roberts,Jean Zhao
申请号：
US16695343
公开号：
US20200291085A1
申请日:
2019.11.26
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Aspects of the disclosure provide fusion proteins that bind cells expressing one or more target molecules including, for example, one or more cell surface multisubunit signaling receptors (e.g., EGFRvIII-expressing cells that also express interferon receptors) and that induce anti-proliferative effects, and related compositions and methods for the treatment of cancer
