Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases

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专利权人:

ATYR PHARMA INC.

发明人:

WATKINS JEFFRY D.,MENDLEIN JOHN D.,HONG FEI,GREENE LESLIE ANN,CHIANG KYLE P.,VASSEROT ALAIN P.,QUINN CHERYL L.,LO WING-SZE

申请号：

NZ60381111

公开号：

NZ603811A

申请日:

2011.07.11

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

Discloses a therapeutic composition, comprising an isolated aminoacyl-tRNA synthetase (AARS) polypeptide of up to 300 amino acids in length that comprises SEQ ID NO: 16 or 14 or an amino acid sequence that is at least 90% identical to SEQ ID NO: 16 or 14, wherein the AARS polypeptide has an extracellular signalling activity and a solubility of at least about 5 mg/mL, and wherein the composition has a purity of at least about 95% on a protein basis and less than about 10 EU endotoxin / mg protein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/