CHIANG KYLE P.,LO WING-SZE,GREENE LESLIE ANN,VASSEROT ALAIN P.,QUINN CHERYL L.,WATKINS JEFFRY D.,HONG FEI,MENDLEIN JOHN D.
申请号：
NZ60381311
公开号：
NZ603813A
申请日:
2011.07.12
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
A therapeutic composition, comprising an isolated amino acyl-tRNA synthetase (AARS) polypeptide of up to about 300 amino acids in length that comprises SEQ ID NO: 12 or 34 or an amino acid sequence that is at least 90% identical to SEQ ID NO: 12 or 34, wherein the AARS polypeptide has an extracellular signalling activity and a solubility of at least about 5 mg/mL, and wherein the composition has a purity of at least about 95% on a protein basis and less than about 10 EU endotoxin / mg protein.
