ORENGO, Jamie M.,ALLINNE, Jeanne,MURPHY, Andrew J.,YANCOPOULOS, George D.
申请号：
PH12019501120
公开号：
PH12019501120A1
申请日:
2019.05.20
申请国别(地区):
PH
年份:
2019
代理人:
摘要：
The present invention provides methods for treating inflammatory diseases, or conditions associated with, or resulting in part from, elevated levels of IL-33 and IL-4, in particular inflammatory lung disorders. The methods of the present invention comprise administering to a subject in need thereof one or more therapeutically effective doses of an IL-33 antagonist alone or in combination with one or more therapeutically effective doses of an IL-4R antagonist. In certain embodiments, the methods of the present invention include use of the antagonists to treat any inflammatory disease or condition mediated in part by enhanced IL-33-mediated signaling and IL-4-mediated signaling.
