SKEPPER, COLIN KEITH,RIVKIN, ALEXEY,MOSER, HEINZ ERNST,MERGO, WOSENU,LAPOINTE, GUILLAUME
申请号：
ARP180101124
公开号：
AR111658A1
申请日:
2018.05.02
申请国别(地区):
AR
年份:
2019
代理人:
摘要：
Useful compounds and pharmaceutical ingredients as antimicrobial agents. These compounds can be used as bacterial guides and inhibitors of bacterial infections. It also provides drug synthesis including these compounds, as well as compounds and components used to treat bacterial infections. Claim 1: A formula compound (1),Where: Z1 is selected from a group of O, S and NHR1.Y C (R1) 832222；Z2 was selected from C(R1)832222.O-(R1) 832222-C (R1) 8322-,A link from Z1 to Z32. The condition is that Z2 is O and Z1 is C (R1) 832222.ZES C (R1) 832222；E.R1 independently selected C8321833183323 in each case, and could be replaced by up to three groups of halos, hydroxyl groups and Alcoxi C832183838323.R3 was selected from the H-L-1-Or2 group.- 1-CN-1-n(r2)832222,-1-Coor2,- 1-Con(r2)832222,- 1-n(r2)c(o)r2,- 1-N(R 2)c(o)o r-1-So8322； -R-1-N(R 2) -So83222R, Y-L-1-So83222N (R 2)；A. Each L1 is a link, or a C83218331838324 linear or linked tar chain； each R is an independent C8321838383832431 tar, replaced by one or three selected groups of halogens；CN, NH832222,- NH (Apartment No. C832131)；- N (Lessor No. C832131 832424) 832222；- So832222 (base address C832131) and Oxo； each R2 is an independent alternative to H or C83218331833183838324, which can be replaced by at most three selected halogens - OH, Alcox C8321833183244；CN-Nr-r- SO83228R and Oxo, or two R2 in the same nitrogen, can form a heterocyclic ring composed of 4-6 members, optionally containing additional heterocyclic atoms selected from N. O and S are ring members and can be replaced by up to three selected halogens - oh, tar C832183318324；Alcoxi C8321883318324248A,CN-Nr-rE.Y.Oxo； R83088 was selected from a group of H, Halo, Acquiro C83218331832626.Halogenated tar C83218338324248A,Lamb.- lz-cn. -lz-n (r2) 832222,Y-l2-Nr2(o) -r2；2. Each L2 shall independently select a chain and a linear or branched C832131 asphalt chain.R830909E was selected from H, HALO, AMINO, CN and C1-83318324A1 groups.Alcoxi C8321883318324248A,A. Haloge
