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CHLORAMPHENICOL ACETYL TRANSFERASE (CAT)-DEFECTIVE SOMATOSTATIN FUSION PROTEIN AND USES THEREOF
专利权人:
BRAASCH BIOTECH LLC
发明人:
MENDELSOHN, ANDREW R,HAFFER, KEITH N,LARRICK, JAMES
申请号:
NZ59001108
公开号:
NZ590011A
申请日:
2008.06.25
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a chimeric polypeptide having the immunogenicity of somatostatin, comprising: an amino acid sequence of somatostatin-14 represented by SEQ ID NO: 1 linked to a substantially inactive and truncated chloramphenicol acetyl transferase polypeptide having a sequence selected from the group consisting of SEQ ID NO: 3, SEQ ID NO: 7, and SEQ ID NO: 8, wherein the somatostatin-14 is linked to the inactive chloramphenicol acetyl transferase by a spacer sequence selected from SEQ ID NO: 10 or SEQ ID NO: 11.
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