PRITCHARD, Joyce,MEBATSION, Teshome,BUBLOT, Michel
申请号：
PH12014502085
公开号：
PH12014502085B1
申请日:
2014.09.22
申请国别(地区):
PH
年份:
2014
代理人:
摘要：
The present invention provides an effective vaccine for Marek's disease, which may be prepared using a recombinant Marek's Disease Virus (MDV), strain CVI988, having been transformed with a foreign DNA construct that includes a long terminal repeat sequence of a reticuloendotheliosis virus. This safe viral agent elicits a highly protective immune response in a chicken against virulent MDV challenge without causing a significant degree of pathogenicity. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent, along with a pharmaceutically acceptable carrier or diluent.
