PRITCHARD, JOYCE,MEBATSION, TESHOME,BUBLOT, MICHEL
申请号:
CA2868099
公开号:
CA2868099A1
申请日:
2013.03.15
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention provides an effective vaccine for Mareks disease, which may be prepared using a recombinant Mareks Disease Virus (MDV), strain CVI988, having been transformed with a foreign DNA construct that includes a long terminal repeat sequence of a reticuloendotheliosis virus. This safe viral agent elicits a highly protective immune response in a chicken against virulent MDV challenge without causing a significant degree of pathogenicity. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent, along with a pharmaceutically acceptable carrier or diluent.