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NOVEL OCTAHYDROPYRIDOQUINAZOLINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES FOR SAID DERIVATIVE AND COMPOSITION
专利权人:
Kissei Pharmaceutical Co.; Ltd.
发明人:
NISHIMURA, Toshihiro,UENO, Yasunori,KASAI, Kiyoshi,YOSHIDA, Masako
申请号:
EP13862652
公开号:
EP2930175A4
申请日:
2013.12.06
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
[Problem] To provide a novel compound that exhibits an agonistic effect on dopamine D 2 receptors. [Solution] The present invention provides a compound represented by the general formula (I): in which R 1 is C 1-6 alkyl or the like R 2 is hydrogen or the like R 3 and R 4 are each hydrogen, C 1-6 alkyl, R 10 R 11 N-C 1-6 alkyl, aralkyl, or the like R 5 and R 6 are hydrogen or the like and R 7 is hydrogen or the like, or a pharmaceutically acceptable salt thereof, a pharmaceutical compositions containing same and uses for said compound/salt and composition. The compounds of the present invention exhibit potent dopamine D 2 receptor simulating activities and thus are useful as a treating or preventing agent for Parkinsons disease and the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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