Toshihiro NISHIMURA,Yasunori UENO,Kiyoshi KASAI,Masako YOSHIDA
申请号：
US14650786
公开号：
US20150315183A1
申请日:
2013.12.06
申请国别(地区):
US
年份:
2015
代理人:
摘要：
[Problem] To provide a novel compound that exhibits an agonistic effect on dopamine D2 receptors.[Solution] The present invention provides a compound represented by the general formula (I):in which R1 is C1-6 alkyl or the like R2 is hydrogen or the like R3 and R4 are each hydrogen, C1-6 alkyl, R10R11N—C1-6 alkyl, aralkyl, or the like R5 and R6 are hydrogen or the like and R7 is hydrogen or the like, or a pharmaceutically acceptable salt thereof, a pharmaceutical compositions containing same and uses for said compound/salt and composition. The compounds of the present invention exhibit potent dopamine D2 receptor simulating activities and thus are useful as a treating or preventing agent for Parkinsons disease and the like.
