Quinolinyl glucagon receptor modulators

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专利权人:

PFIZER INC.

发明人:

GUZMAN-PEREZ ANGEL,DIDIUK MARY,FILIPSKI KEVIN J.,LEE ESTHER C.,PFEFFERKORN JEFFREY A.,STEVENS BENJAMIN,TU MEIHUA

申请号：

NZ62002212

公开号：

NZ620022A

申请日:

2012.07.12

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

Provided are quinolinyl derivative compounds of general formula I, where the variables are as defined in the specification. Examples of the compounds include (+/-)-3-(4-(1-(3-methylquinolin-2-ylamino)butyl)benzamido)propanoic acid and (+/-)-3-{ 4-[3-methyl-1-(quinoxalin-2-ylamino )-butyl]-benzoylamino} -propionic acid. The compounds act as glucagon antagonists or inverse agonists. The compounds may be useful in the treatment of diabetes.

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