DERIVE DE TETRAHYDROISOQUINOLIN-1-ONE OU SEL DE CELUI-CI

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专利权人:

ASTELLAS PHARMA INC.

发明人:

HISAMICHI, HIROYUKI,SHIMADA, ITSURO,ISHIHARA, TSUKASA,TAKUWA, TOMOFUMI,SHIMIZU, TAKAFUMI,ISHIKAWA, NORIKO,MAENO, KYOICHI,SEKI, NORIO

申请号：

CA2688326

公开号：

CA2688326C

申请日:

2008.05.26

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

Tetrahydroisoquinolin-1-one derivatives having an amide group at position-4 orapharmaceutically acceptable salt thereof have an excellent antagonisticactivity on a bombesin-2(BB2) receptor. These compounds are also highly effective on stoolabnormality. Therefore, thesetetrahydroisoquinolin-1-one derivatives are useful as therapeutic agents fordiseases associated with aBB2 receptor, particularly IBS.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/