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נגזרת טטראהידרואיזוקווינולין–1–און או מלח שלה
专利权人:
ASTELLAS PHARMA INC.;SELDAR PHARMA INC.
发明人:
申请号:
IL20230109
公开号:
IL202301A
申请日:
2009.11.24
申请国别(地区):
IL
年份:
2017
代理人:
摘要:
[Problems] To provide a pharmaceutical, in particular a compound which can be used as a therapeutic agent for irritable bowel syndrome (IBS). [Means for Solving Problems] It was found that a tetrahydroisoquinolin-1-one derivative having an amide group at the 4-position or a pharmaceutically acceptable salt thereof has an excellent bombesin 2 (BB2) receptor antagonistic action. It is also found that the tetrahydroisoquinolin-1-one derivative is highly effective on bowel movement disorders. From the above, the tetrahydroisoquinolin-1-one derivative of the present invention is useful as a therapeutic agent for diseases associated with a BB2 receptor, in particular IBS.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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