KANG HEE CHOL,GEE KYLE,MANDAVILLI BHASKAR,YING Lai Qiang,BRANCHAUD BRUCE
申请号：
IN3324/CHENP/2013
公开号：
IN2013CN03324A
申请日:
2013.04.29
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
ABSTRACT Described herein are compounds compositions methods and kits for detecting reactive oxygen species (ROS) by conventional fluorescence microscopy fluorescence spectroscopy flow cytometry and/or high content imaging. The compounds disclosed herein are novel reduced dyes including Cy based hydrocyanine dyes and Cy based deuterocyanine dyes which dyes are probes for detecting ROS and measuring oxidative stress in cells either in vitro and/or in vivo. Also described herein are processes for preparing novel reduced dyes i.e. ROS probes for use in the disclosed compositions methods and kits.
