The present invention relates to compounds of Formula (I) and/or Formula (Ia):and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit ALK kinase activity, and thus may be used for the treatment of cancer.本發明係關於式(I)及/或式(Ia)之化合物:及其鹽,醫藥組合物,使用方法及其製備方法。該等化合物抑制ALK激酶活性且因此可用於治療癌症。