(57)< Abstract > This invention the deviation from to cell regards the method of producing the portion of the internal organs or the internal organs which are converted. Without destroying the between quality structure of the said internal organs removing the cell membrane which surrounds the said isolated internal organs with mechanical shaking making use of the internal organs which are isolated, it produces the deviation from cell conversion internal organs. After removing the cell membrane, said the internal organs which are isolated without melting the between quality structure of the said internal organs exposing to the solubilization liquid which extracts the cell substance. Leaving the deviation from cell conversion internal organs making use of the liquid for washing, it removes the solubility component.本発明は脱細胞化した臓器または臓器の一部を製造する方法に関する。脱細胞化臓器は単離した臓器を用い、機械的揺動で該臓器の間質構造を破壊せずに該単離臓器を取り囲む細胞膜を除去して製造する。細胞膜を除去した後、該単離した臓器を該臓器の間質構造を溶解せずに細胞物質を抽出する可溶化液体に曝す。洗浄用液体を用い脱細胞化臓器を残して可溶性成分を除去する。