NANOPARTICULES CONJUGUEES A UN AGENT ANTINUCLEOLINE EN TANT QUE RADIOSENSIBILISEURS ET AGENTS DE CONTRASTE D'IMAGERIE PAR RESONANCE MAGNETIQUE (IRM) ET/OU EN RAYONS X
THE UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION; INC.
发明人:
MALIK, MOHAMMAD TARIQ,O'TOOLE, MARTIN G.,BATES, PAULA J.,OTOOLE, MARTIN G.
申请号：
CA3020885
公开号：
CA3020885A1
申请日:
2016.05.05
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
A composition comprises an anti-nucleolin agent conjugated to nanoparticles, and optionally containing gadolinium. Furthermore, a pharmaceutical composition for treating cancer comprises a composition including an anti-nucleolin agent conjugated to nanoparticles, and a pharmaceutically acceptable carrier. The composition enhances the effectiveness of radiation therapy, enhancing contrast in X-ray imaging techniques, and when gadolinium is present, provide cancer selective MRI contrast agents.
