NANOPARTICULES SUPERPARAMAGNÉTIQUES UTILISÉES EN TANT QU'AGENT DE CONTRASTE DANS L'IMAGERIE PAR RÉSONANCE MAGNÉTIQUE (IRM) DE SUSCEPTIBILITÉ MAGNÉTIQUE (T2*)
CERDAN GARCIA-ESTELLER, SEBASTIÁN,CALLE HERNÁNDEZ, DANIEL,MORENO EGEA, FERNANDO
申请号：
EP12866960
公开号：
EP2808036A4
申请日:
2012.01.27
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The invention relates to the use of biocompatible superparamagnetic nanoparticles comprising an inorganic core and a coating including an electrically charged polymer, and having low tissue and vascular adhesion, for use as contrast agents in magnetic resonance imaging (MRI). The aforementioned nanoparticles have novel pharmacokinetic and relaxability T2* properties, with high potential for use in in vivo tissue imaging and tumour perfusion strategies based on parameter T2*.
