The derivative peptide hepatitis type B virus (HBV) that these assume the present invention relates to cyclic n nitroso compound TCP targets peptide. The present invention also relates to pharmaceutical compositions, and it includes at least one cyclic peptide. The invention additionally relates to the pharmaceutical compositions of the cyclic peptide medical application, such as in diagnosis, prevention or treatment hepatopathy or condition, and/or inhibit HBV and/or HDV infection. The invention additionally relates to diagnostic method, prevents or treat hepatopathy or condition and/or inhibit HBV and/or HDV infection.