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CYCLIC NTCP-TARGETING PEPTIDES AND THEIR USES AS ENTRY INHIBITORS
专利权人:
Ruprecht-Karls-Universität Heidelberg
发明人:
Stephan URBAN,Yi NI,Walter MIER
申请号:
US15780129
公开号:
US20180354993A1
申请日:
2016.12.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to cyclic NTCP targeting peptides which are preS-derived peptides of hepatitis B virus (HBV). The present invention further relates to pharmaceutical compositions comprising at least one cyclic peptide. The present invention further relates to medical uses of said cyclic peptides and the pharmaceutical compositions, such as in the diagnosis, prevention and/or treatment of a liver disease or condition, and/or in the inhibition of HBV and/or HDV infection. The present invention further relates to methods of diagnosis, prevention and/or treatment of a liver disease or condition and/or the inhibition of HBV and/or HDV infection.
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