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DERIVE DE 1-(CYCLOALKYL-CARBONYL)PROLINE
专利权人:
LTD.;SUMITOMO DAINIPPON PHARMA CO.
发明人:
IKUMA, YOHEI,FUKUDA, NOBUHISA,IWATA, MASATO,KIMURA, HIDENORI,SUZUKI, KUNIKO
申请号:
CA2881566
公开号:
CA2881566A1
申请日:
2013.07.18
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
A compound represented by formula (1) (in the formula: ring-D represents a three- to eight-membered hydrocarbon ring; Ra represents an optionally substituted amino C1-6 alkyl group or the like; Rb1 and Rb2 each independently represent a hydrogen atom, a halogen atom, or the like; Rc represents an optionally substituted C6-10 aryl group or the like; Rd represents a hydrogen atom or the like; and ring-Q represents a (hetero)aryl group or the like which may be substituted with a carboxyl group or the like) or a pharmaceutically acceptable salt thereof exhibits an excellent FXIa inhibitory activity, and is useful as a therapeutic agent against thrombosis or the like.
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