The present invention provides a use of a composition for preparing a medicine for treating symptoms or disorders of collagen abnormal proliferation following peritoneal and/or peritoneal cover organ damage in an individual in need thereof, wherein the composition comprises umbilical cord mesenchymal stem cells. The present invention also provides a composition for preparing a medicine for treating symptoms or disorders of collagen abnormal proliferation following peritoneal and/or peritoneal cover organ damage in an individual in need thereof, wherein the composition comprises an umbilical cord mesenchymal stem cell exsosome.本發明提供一種組合物用於製備在有需求之個體治療腹膜及/或腹膜覆蓋器官受損後膠原蛋白異常增生之症狀或病症之藥物的用途,其中該組合物係包含臍帶間質幹細胞。本發明並提供一種組合物用於製備在有需求之個體治療腹膜及/或腹膜覆蓋器官受損後膠原蛋白異常增生之症狀或病症之藥物的用途,其中該組合物係包含臍帶間質幹細胞外泌體。