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Pharmaceutical formulation comprising ezetimibe
专利权人:
Ganesh Gat;Pasupuleti Giridhara Rao;Javed Hussain
发明人:
Ganesh Gat,Pasupuleti Giridhara Rao,Javed Hussain
申请号:
US12747270
公开号:
US08858994B2
申请日:
2008.12.09
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to novel formulations comprising ezetimibe as active ingredient. In particular the invention relates to a pharmaceutical composition comprising 5 to 20 wt-% ezetimibe, 50 to 85 wt-% diluent, 3 to 25 wt-% disintegrant, 1 to 10 wt-% binder, and 0.5 to 1 wt-% lubricant, characterized in that the ezetimibe has a particle size distribution of d(0.9) of 5 μm to 35 μm and d(0.5) of 3 μm to 20 μm, as well as methods for preparing said formulations.
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