Methods for increasing thermogenic adipocytes

• 收藏
• 分享

专利权人:

发明人:

John Knopf,Jasbir Seehra,Ravindra Kumar

申请号：

US14242212

公开号：

US09790284B2

申请日:

2014.04.01

申请国别(地区):

US

年份:

2017

代理人:

摘要：

In certain aspects, the present invention provides compositions and methods for increasing thermogenic adipocytes (e.g., brown adipocytes or other UCP-1 expressing adipocytes) by administering an antagonist of an ActRIIB signaling pathway. Examples of such antagonists include ActRIIB polypeptides, anti-ActRIIB antibodies, anti-myostatin antibodies, anti-GDF3 antibodies, anti-Noda1, anti-activin, and anti-GDF11 antibodies. A variety of metabolic and other disorders may be treated by causing an increase in thermogenic adipocytes.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/