Bee Eng Mary Chan,Jinye Shen,Bin He,Aiping Zhu,Yehai Yan,Chee Yoon Yue
申请号：
US11176654
公开号：
US08906282B2
申请日:
2005.07.06
申请国别(地区):
US
年份:
2014
代理人:
摘要：
In embodiments of the present invention, a biodegradable/biodegradable polymer film may be used as a scaffold for tissue engineering scaffolds for engineering organized organs, such as vascular grafts, for example. In one embodiment, an ultraviolet (UV) resin made from a diacrylated biodegradable oligomer is molded into a flexible scaffold having cavities and/or channels. Channel/cavity size may be on the order of micrometers and/or nanometers, and thus the walls may have high aspect ratios. Smooth muscle cells may be deposited in the channels and because of the high aspect ratios, the cells may align along the channels/cavities as confluence is reached.
