Compounds derived from 3 - (imidazo [4,5-c] pyridin-2-yl) - indazol, inhibitors of one or more proteins in the WNT signaling Pathway； Pharmaceutical Composition and method of treatment of a disorder or disease that is involved in the Aberrant WNT signaling such as cancer, osteoartriti S and Alzheimer's disease, among others.
Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.<；p>；El compuesto (N-(5-(3-(7-(3-FLUOROFENIL)-3H-IMIDAZOL[4,5-c]-PIRIDIN-2-IL)-1H-INDAZOL-5-IL)-PIRIDIN-3-IL)-3-METILBUTANAMIDA), INHIBIDORES DE PROTEÍ；NAS EN LA RUTA DE SEÑ；ALIZACIÓ；N DE Wnt； COMPOSICIÓ；N FARMACÉ；UTICA； Ú；TILES PARA EL TRATAMIENTO DEL CÁ；NCER, RETINOPATÍ；A DIABÉ；TICA, FIBROSIS PULMONAR, ARTRITIS REUMATIDE, ESCLERODERMIA, ENTRE OTRAS.<；/p>；
