Compounds derived from indazol - 3 - carboxamidas, as inhibitors of the Signaling Pathway of Wnt / - catenin B； Pharmaceutical composition that comprises； and its use for the treatment of cancer, rheumatoid arthritis, viral and fungal infections, Parkinson's disease, fibrotic disorders, Among other diseases.
Indazole-3-carboxamide compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole-3-carboxamide compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.COMPUESTOS DERIVADOS DE INDAZOL-3-CARBOXAMIDAS, INHIBIDORES DE LA RUTA DE SEÑALIZACION DE WNT/B-CATENINA； COMPOSICION FARMACEUTICA； Y USO PARA EL TRATAMIENTO DE CANCER, ARTRITIS REUMATOIDE, INFECCIONES MICOTICAS Y VIRICAS, ENFERMEDAD DE PARKINSON, UN TRASTORNO FIBROTICO, ENTRE OTRAS ENFERMEDADES.
