In radiation therapy, treatment objectives applicable to different identified structures in a patient's body (e.g., a target structure and an organ at risk (OAR)) may conflict due to overlap between the structures. Automated systems and methods can detect and resolve such conflicts. For example, a set of modified regions that do not overlap with each other can be defined at 708, and a modified treatment objective 708 for each modified region can be determined based on the original treatment objectives. The modified regions and modified treatment objectives can be used in treatment planning processes.
