THORARENSEN, ATLI,BROWN, MATTHEW FRANK,CASIMIRO-GARCIA, AGUSTIN,CHE, YE,FLANAGAN, MARK EDWARD,GILBERT, ADAM MATTHEW,HAYWARD, MATTHEW MERRILL,TELLIEZ, JEAN-BAPTISTE,UNWALLA, RAYOMAND JAL,TRUJILLO, JOHN
申请号:
CA2984183
公开号:
CA2984183A1
申请日:
2016.04.19
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention provides pharmaceutically active pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3- b]pyrazinyl,and pyrrolo[2,3-b]pyridinyl acrylamides, epoxides,and analogues thereof. Such compounds are useful for inhibiting Janus Kinase (JAK). This invention also is directed to compositions comprising methods for making such compounds, and methods for treating and preventing conditions mediated by JAK.