FISCHETTI, VINCENT, A.,SCHMITZ, JONATHAN,GILMER, DANIEL,EULER, CHAD
申请号:
EP12773653
公开号:
EP2699253A4
申请日:
2012.04.20
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including Streptococcus and Staphylococcus , and related conditions. The invention provides compositions and methods incorporating and utilizing Streptococcus suis derived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided.