Veronique Mathieu,Gwendoline Van Goietsenoven,Jacques Dubois,Florence Lefranc-Kiss,Laurent Ingrassia,Robert Kiss
申请号：
US13695609
公开号：
US20130053347A1
申请日:
2010.05.03
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to the biology and mechanism of action of the naturally occurring compound Narciclasine, especially as an anti-cancer agent for brain tumors. The invention provides new insights on the target molecule of Amaryllidaceae isocarbostyril derivatives as for example Narciclasine and provides new prodrugs of these Amaryllidceae isocabostyril constituents for treating cancer, specifically cancers or tumors located in the brain.
