NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION
发明人:
HU, YOA PU,胡幼圃,胡幼圃,LEE, JR TING,李芷葶,李芷葶,SHIH, TUNG YUAN,石东原,石東原
申请号：
TW103128908
公开号：
TW201607530A
申请日:
2014.08.22
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
This invention relates to a safety compound composition used for treating symptom of non-alcoholic fatty liver disease (NAFLD) without side effect, the compound composition being selected from at least one or any combination in the group composed of the following bioflavonoids: (-)-Epicetechin-3-gallate, Paeoniflorin, Isorhmnetin, Eicosapentaenoic acid ethyl ester, Quercetin, phlorizin, (-)-Epigallocetechin, Quercitrin, Hesperetin, (-)-Epigallocetechin-3-gallate, Gallic acid, Kaempferol, Hesperidin, Puerarin, Silibinin, Formononetin, Baicalein, Nordihydroguaiaretic acid, Baicalin, Dihydroxycoumarin, Daidzin, Glycyrrhizin, 6-Gingerol, Rutin, Liquiritin, Phloretin, Daidzein, Umbelliferone, Genistein, (-)-Epicatechin, Naringin, Neohesperidin, Wogonin, Capillarisin, Isoliquiritigenin, and Ursolic acid, which is used for treating symptom of NAFLD. Furthermore, this invention also provides an application of manufacturing pharmaceuticals for reducing symptoms of liver fat and blood fat by using novel compound composition used for treating symptom of NAFLD.一種用於治療非酒精性脂肪肝疾病(Non-alcoholic Fatty Liver Disease,NAFLD)症狀之安全無副作用化合物組合物,其中該化合物組合物係選自下列生物類黃酮化合物(bioflavonoids)所組成群組中之至少一種或其任意組合:(-)-Epicetechin-3-gallate、芍藥苷、異鼠李素、二十碳五烯酸乙酯、槲皮素、根皮苷、(-)-Epigallocetechin、槲皮、橙皮素、(-)-Epigallocetechin-3-gallate、沒食子酸、山奈酚、橙皮苷、葛根素、水飛薊賓、芒柄花黃素、黄芩素、正二羥癒瘡酸、黄芩、二羥基香豆素、大豆苷、甘草甜素、6-薑辣醇、芸香素)、甘草苷、根皮素、大豆苷元、傘形花內酯、金雀異黃酮、(-)-Epicatechin、柚皮苷、新橙皮苷、漢黃芩素、茵陳色原酮、異甘草素與熊果酸,用於治療非酒精性脂肪肝疾病之症狀。更進一步,本發明亦提供一種以新穎治療非酒精性脂肪肝疾病之化合物組成物用於製造降低肝臟脂肪、血脂肪症狀的藥劑之用途。
