The invention provides novel imidazo[1,2-b]pyridazines of formula (I) and pharmaceutically acceptable salts, polymorphs, hydrates, tautomers, solvates and stereoisomers thereof.Compounds of formula (I) are useful for treating or preventing diseases associated with GABAA receptor modulation, anxiety, epilepsy, sleep disorders including insomnia, and for inducing sedation-hypnosis, anesthesia, sleep and muscle relaxation.The invention also provides synthetic procedures for preparing said compounds and certain intermediates, as well as intermediates themselves.本發明提供新穎式(I)之咪唑并[1,2－b]嗒類和其醫藥上可接受的鹽、多形體(polymorphs)、水合物、互變異構物、溶劑合物和立體異構物。式(I)之化合物有用於治療或預防與GABAA體調節有關之疾病、焦慮、癲癇症、包括失眠症之睡眠障礙、及用於誘導鎮靜－催眠、麻醉、睡眠和肌肉放鬆。本發明也提供製備該等化合物及某些中間物之合成步驟，以及中間物本身。
