FALCO, JOSE LUIS,PALOMER, ALBERT,GUGLIETTA, ANTONIO
申请号:
CA2647116
公开号:
CA2647116C
申请日:
2007.03.28
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention provides novel imidazo[1,2-b]pyridazines of formula (I) and pharmaceutically acceptable salts, polymorphs, hydrates, tautomers, solvates and stereoisomers thereof. Compounds of formula (I) are useful for treating or preventing diseases associated with GABAA receptors modulation, anxiety, epilepsy, sleep disorders including insomnia, and for inducing sedation-hypnosis, anesthesia, sleep and muscle relaxation. The invention also provides synthetic procedures for preparing said compounds and certain intermediates, as well as intermediates themselves.