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Imidazo[1,2-b]pyridazines, processes, uses, intermediates and compositions
专利权人:
Antonio Guglietta;José Luís Falcó;Albert Palomer
发明人:
José Luís Falcó,Albert Palomer,Antonio Guglietta
申请号:
US12225740
公开号:
US08153789B2
申请日:
2007.03.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides novel imidazo[1,2-b]pyridazines of formula (I) and pharmaceutically acceptable salts, polymorphs, hydrates, tautomers, solvates and stereoisomers thereof.Compounds of formula (I) are useful for treating or preventing diseases associated with GABAA receptors modulation, anxiety, epilepsy, sleep disorders including insomnia, and for inducing sedation-hypnosis, anesthesia, sleep and muscle relaxation.The invention also provides synthetic procedures for preparing said compounds and certain intermediates, as well as intermediates themselves.
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