BACHMANN MARTIN,JEGERLEHNER ANDREA,SAUDAN PHILIPPE
申请号：
IN7586/CHENP/2011
公开号：
IN2011CN07586A
申请日:
2011.10.19
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
The present invention is in the fields of medicine public health immunology molecular biology and virology. The invention provides compositions vaccine compositions and pharmaceutical compositions for the treatment amelioration and / or prevention of influenza. The compositions vaccine compositions and pharmaceutical compositions of the invention comprise a virus-like particle of an RNA bacteriophage and at least one antigen wherein said at least one antigen is an ectodomain of an influenza virus hemagglutinin protein or a fragment of said ectodomain of an influenza virus hemagglutinin protein. When administered to an animal preferably to a human said compositions vaccine compositions and pharmaceutical compositions efficiently induce immune responses in particular antibody responses wherein typically and preferably said antibody responses are directed against influenza virus. Thus the invention further provides methods of treating ameliorating and / or preventing influenza virus infection.
