The present invention relates to pharmaceutical industry and can find application in the production of medicinal and health-improvement agents, of compositions for medical purposes, of biologically active additives, of veterinary compositions, etc.The technical result achieved lies in the obtaining of drugs and biologically active agents in which pharmaceutical ingredients are present in a reduced condition, stable in time, that involves their increase in affinity to the chemical form of the active ingredient (reduced condition), when it gets into biological fluids of a living organism (into blood, lymph, cellular and intracellular fluids).Said technical result is obtained thanks to the fact that in the process for producing liquid-base drugs and biologically active agents, comprising dissolving in a liquid medium of at least one active pharmaceutical ingredient taken in a pharmaceutically active amount, as the liquid medium, use is made of an aqueous solution of potassium and sodium bicarbonates taken in a ratio corresponding to their mean content in the organism internal fluids. Preferably, after dissolving the sodium and potassium bicarbonates, the sodium ions to the potassium ions ratio in the liquid medium should be of (2-6): 1.Said technical result is obtained as well by the fact that when producing compositions comprising more than one active pharmaceutical ingredient, an active pharmaceutical ingredient with an alkaline base is dissolved first, then an active pharmaceutical ingredient with an acid or neutral base or an agent demonstrating high biological activity is dissolved, the redox potential of liquid-base drugs and biologically active agents being preferably not more than 0 mV. In this case, the pharmaceutical ingredients of the composition can be introduced into the aqueous solution with the redox potential lowered to a value of no more than 0 mV, or initially all the pharmaceutical ingredients according to the formulation can be introduced into an aq
