Dewayne Townsend;Daniel E. Michele;Soichiro Yasuda;Joseph M. Metzger
发明人:
Joseph M. Metzger,Dewayne Townsend,Soichiro Yasuda,Daniel E. Michele
申请号:
US12915352
公开号:
US08580245B2
申请日:
2010.10.29
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to compositions and methods for treating and preventing heart disease. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing heart disease (e.g., in subjects with muscular dystrophy) and for treating cells and tissue damage caused by ischemia and cell death (e.g., for treating dystrophin-deficient cells (e.g., myocytes)).