Bruce Markham;Rainer Ng;Lorraine Reeve;Joseph M. Metzger
发明人:
Rainer Ng,Joseph M. Metzger,Lorraine Reeve,Bruce Markham
申请号:
US12747073
公开号:
US08852568B2
申请日:
2008.12.17
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to compositions and methods for treating and preventing skeletal muscle deficiencies. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing skeletal muscle deficiencies and injuries (e.g., dystrophin-deficient skeletal muscle; skeletal muscle having a contraction force deficit; skeletal muscle having a Ca2+ imbalance; skeletal muscle having microtears).