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Composition comprising vemurafenib and HPMC-AS
专利权人:
ratiopharm GmbH
发明人:
Lehmann, Frank,Guserle, Richard,Albrecht, Wolfgang
申请号:
ES15160958
公开号:
ES2642162T3
申请日:
2015.03.26
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
The present invention relates to a premix comprising vemurafenib, in particular vemurafenib hydrochloride, and hydroxypropyl methyl cellulose acetate succinate, which is herein referred to as HPMC-AS in a specific weight ratio and to oral dosage forms comprising said premix. Further, the invention relates to a process for producing said premix comprising vemurafenib hydrochloride and HPMC-AS and to the corresponding process of producing an oral dosage form containing the premix of the invention.
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