603207 Disclosed is a pharmaceutical composition and a combination product comprising Roflumilast also known as 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4- (difluoromethoxy)benzamide； and either simvastatin also known as (1S,3R,7S,8S,8aR)-8-{ 2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl} -3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate or atorvastatin also known as (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid； and a pharmaceutically acceptable auxiliary. In the combination product the two actives are adapted for simultaneous or sequential administration. Also disclosed is the process for making the composition and the use of the composition for the manufacture of a medicament for the treatment of an inflammatory pulmonary disease.
