Bryan C. BARNHART,Brigitte DEVAUX,Aaron P. YAMNIUK,Shannon L. OKADA,Brenda L. STEVENS
申请号：
US15579450
公开号：
US20180142030A1
申请日:
2016.06.28
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided herein are agonistic antibodies, or antigen binding portions thereof, that bind to human CD40. Such antibodies optionally comprise Fc regions with enhanced specificity for FcγRIIb. The invention also provides methods of treatment of cancer or chronic infection by administering the antibodies of the invention to a subject in need thereof.
